Description
5-Amino-1MQ is a small, membrane-permeable molecule derivative of methylquinolinium. In laboratory settings, it is primarily investigated for its capacity to inhibit the enzyme Nicotinamide N-methyltransferase (NNMT). NNMT is a cytosolic enzyme that plays a critical role in cellular metabolism, particularly in the regulation of nicotinamide adenine dinucleotide (NAD+) salvage pathways and adipose tissue function.
Scientific literature focuses extensively on 5-Amino-1MQ as a tool to explore the downstream effects of NNMT inhibition. By blocking this enzyme, researchers study potential shifts in cellular energy expenditure, the optimization of NAD+ levels, and the modulation of lipogenesis (fat accumulation). It is a key compound in experiments aiming to understand the molecular basis of obesity, metabolic syndrome, and age-related decline in cellular function in non-human models.
- This material is strictly for laboratory research use only —
no instructions for reconstitution, dosing, or administration can be provided.







Reviews
There are no reviews yet.